Dipankar Bhattacharyya

نویسندگان

  • Dipankar Bhattacharyya
  • Utpalendu Jana
  • Pratip Kumar Debnath
  • Tapas Kumar Sur
چکیده

Valeriana wallichii, an Indian medicinal plant, has been on trial for its role in stress disorders in hospital based clinical set-up. Hamilton’s Brief Psychiatric Rating Scale (BPRS) was used and thorough clinical investigations were carried out to screen the subjects. Thirty-three subjects (20 male and 13 female; average age 34.2 years) were medicated with the plant extract in a fixed dose regime (500 mg/capsule, twice daily, p.o. after meal). They were thoroughly investigated clinically and using standard questionnaires based on different psychological rating scale at baseline (day 0), mid-term (day 30) and final (day 60). The observations exhibited that, V. wallichii not only significantly (p<0.001) attenuated stress and anxiety, but also significantly (p<0.001) improved depression and also enhanced the willingness to adjustment. Nevertheless it did not alter memory, concentration or attention of the volunteers. The results suggest that V. wallichii may be useful in the treatment of stress related disorders in human and may be a promising antistress agent in near future.

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تاریخ انتشار 2007